GATA2 anticorps

N° du produit ABIN932509

Cet anticorps Souris Monoclonal détecte spécifiquement GATA2 dans ICC et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour GATA2 anticorps (ABIN932509)

Antigène: GATA2 (GATA Binding Protein 2 (GATA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GATA2 est non-conjugé

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 353C5a

Détail du produit anti-GATA2 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: GATA2 antibody was raised in mouse using recombinant Human Gata Binding Protein 2

Isotype: IgG2b

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: GATA2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur GATA2

Antigène: GATA2 (GATA Binding Protein 2 (GATA2))

Autre désignation: GATA2

Sujet: The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. GATA1 is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells. In chicken erythroid progenitors, forced expression of GATA2 promotes proliferation at the expense of differentiation. GATA3 expression is restricted to T-lymphoid cells and some nonhematopoietic cell types, including embryonic stem cells. Synonyms: Monoclonal GATA2 antibody, Anti-GATA2 antibody, GATA binding protein 2 antibody, MGC2306 antibody, NFE1B antibody.

Pathways: Stem Cell Maintenance